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Protein Coding Gene : B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Primary Identifier  MGI:1889505 Organism  Mus musculus
Chromosome  11 NCBI Gene Number  53625
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 5.3.0)

Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Acts upstream of or within several processes, including axon guidance; cellular response to leukemia inhibitory factor; and sensory perception of smell. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and nose. Orthologous to human B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2).
PHENOTYPE: Homozygotes for a gene trap allele show severe axon guidance errors and specific loss of olfactory sensory neurons and glomeruli. Homozygotes for another gene trap allele show hyperactive lymphocytes and macrophages. Homozygotes for a reporter allele display behavioral despair and reduced anxiety. [provided by MGI curators]
  • synonyms:
  • expressed sequence AA409404,
  • AA408337,
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,
  • expressed sequence AA408337,
  • B3Galt6,
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1,
  • expressed sequence AW260308,
  • B3gnt1,
  • B3gnt2,
  • AA409404,
  • MGI:2143995,
  • MGI:1890585,
  • MGI:2144521,
  • AW260308,
  • MGI:2143981

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

369 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications