Primary Identifier | MGI:3611890 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Kcnmb4 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
description | Relationship to Human Syndrome: Temporal lobe epilepsy |
molecularNote | Exon 1 was replaced with an eGFP-SV40-neo cassette. Elimination of the exon results in the loss of approximately half of the protein-coding region, including the first transmembrane domain. Northern blot did not detect transcript of the wild-type, but did detect transcript using an eGFP probe. |