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Allele : Kcnmb4<tm1Rwa> potassium large conductance calcium-activated channel, subfamily M, beta member 4; targeted mutation 1, Richard W Aldrich

Primary Identifier  MGI:3611890 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnmb4
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
description  Relationship to Human Syndrome: Temporal lobe epilepsy
molecularNote  Exon 1 was replaced with an eGFP-SV40-neo cassette. Elimination of the exon results in the loss of approximately half of the protein-coding region, including the first transmembrane domain. Northern blot did not detect transcript of the wild-type, but did detect transcript using an eGFP probe.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • BK-Beta4 null,
  • Beta4<->,
  • BK-Beta4 null,
  • Beta4<->,
  • Beta4 KO,
  • Beta4 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele