Primary Identifier | IPR041031 | Type | Domain |
Short Name | RNF31_C |
description | This is the C-terminal domain of RNF31 (also known as HOIP) from humans. HOIP is a component of the linear ubiquitin chain assembly complex (LUBAC), which synthesizes the linear ubiquitin chains that help control innate immunity and inflammation [, , ]. This region has an RBR domain which catalyzes the transfer of ubiquitin onto a substrate []. |