Primary Identifier | MGI:2661723 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ace2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 9 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region (nt 1069 through 1299) encoded the zinc binding catalytic domain. Northern and Western blot analyses indicated that neither transcript nor protein are produced by the mutant allele. |