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Allele : Ace2<tm1Pngr> angiotensin converting enzyme 2; targeted mutation 1, Josef M Penninger

Primary Identifier  MGI:2661723 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ace2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 9 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region (nt 1069 through 1299) encoded the zinc binding catalytic domain. Northern and Western blot analyses indicated that neither transcript nor protein are produced by the mutant allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

71 Publication categories

Trail: Allele