Primary Identifier | MGI:2149087 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Add2 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced exons 9 to 13. Northern blot analysis using a full-length rat cDNA probe detected transcripts smaller than wild-type in brain and spleen of homozygous animals. Western blot analysis did not detect wild-type or deleted forms of protein in brain, spleen, or erythrocyte ghosts from homozygous mice. |