| First Author | Malergue F | Year | 1998 |
| Journal | Mol Immunol | Volume | 35 |
| Issue | 17 | Pages | 1111-9 |
| PubMed ID | 10395200 | Mgi Jnum | J:53714 |
| Mgi Id | MGI:1333316 | Doi | 10.1016/s0161-5890(98)00102-3 |
| Citation | Malergue F, et al. (1998) A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol Immunol 35(17):1111-9 |
| abstractText | The architecture of lymphoid microenvironments depends upon complex interactions between several stromal cell types. We describe in this report the cloning of a cDNA which encodes a novel membrane molecule containing two external Ig-like domains. It is expressed at the junction between endothelial cells including HEV. It is also expressed by platelets and MHC class II+ antigen presenting cells in thymic medulla and T-cell areas in peripheral lymphoid organs. These cells which lack in RelB-deficient mice include tissue-derived dendritic, epithelial cells and macrophages. Thus, this molecule might contribute to the organization of cell junctions in different microenvironments. |
