| Primary Identifier | MGI:2182918 | Allele Type | Spontaneous |
| Gene | Myo7a | Strain of Origin | B6;SJL-Tg(c177-lacZ)226Bri/J |
| Is Recombinase | false | Is Wild Type | false |
| description | Genetic Background: The 266Bri stock on which Myo7ash1-8J arose was homozygous for a lacZ transgene. The mutation was not the result of the transgene integration, as not all animals exhibited the neurological phenotype. |
| molecularNote | Two genomic regions encompassing a total of about 6.4 kb was deleted n this mutation. One region spans about 3.6 kb and covers exons 38 through 40. The other region spans about 2.8 kb and covers exons 46 and 47. Immunoblot analysis failed to detect protein in extracts from homozygous mice. |
