First Author | Unger AE | Year | 1983 |
Journal | J Hered | Volume | 74 |
Issue | 2 | Pages | 88-92 |
PubMed ID | 6841965 | Mgi Jnum | J:7048 |
Mgi Id | MGI:55519 | Doi | 10.1093/oxfordjournals.jhered.a109747 |
Citation | Unger AE, et al. (1983) Hemolytic anemia in the mouse. Report of a new mutation and clarification of its genetics. J Hered 74(2):88-92 |
abstractText | A new mutation causing spherocytic, hemolytic anemia has been discovered in the house mouse. It is inherited as a single autosomal recessive gene, allelic with both sph and ha, which, in turn, were shown to be allelic with each other. A revised nomenclature for the three apparent alleles is proposed: sph (formerly sph), sphha (formerly ha), and sph2Bc (the new mutation). Like the other murine hemolytic anemias, sph2Bc involves a defect in the red blood cell membrane protein, spectrin. |