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Publication : Hemolytic anemia in the mouse. Report of a new mutation and clarification of its genetics.

First Author  Unger AE Year  1983
Journal  J Hered Volume  74
Issue  2 Pages  88-92
PubMed ID  6841965 Mgi Jnum  J:7048
Mgi Id  MGI:55519 Doi  10.1093/oxfordjournals.jhered.a109747
Citation  Unger AE, et al. (1983) Hemolytic anemia in the mouse. Report of a new mutation and clarification of its genetics. J Hered 74(2):88-92
abstractText  A new mutation causing spherocytic, hemolytic anemia has been discovered in the house mouse. It is inherited as a single autosomal recessive gene, allelic with both sph and ha, which, in turn, were shown to be allelic with each other. A revised nomenclature for the three apparent alleles is proposed: sph (formerly sph), sphha (formerly ha), and sph2Bc (the new mutation). Like the other murine hemolytic anemias, sph2Bc involves a defect in the red blood cell membrane protein, spectrin.
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