| Primary Identifier | MGI:1859778 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 53417 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within response to hypoxia and transcription by RNA polymerase II. Located in mitochondrion and nuclear speck. Is expressed in several structures, including central nervous system; genitourinary system; and lung. Orthologous to human HIF3A (hypoxia inducible factor 3 subunit alpha). PHENOTYPE: Mice homozygous for a knock-out allele display impaired lung remodeling resulting in hypertrophy of the heart right ventricle and pulmonary hyperplasia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
