Primary Identifier | MGI:2177780 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lif |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance gene was inserted into exon 3. Northern blot analysis on embryonic fibroblasts isolated from homozygous embryos demonstrated that no detectable transcript was produced from this allele, and cell growth assays confirmed that no functional protein was expressed from this allele. |