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Allele : Lif<tm1Stw> leukemia inhibitory factor; targeted mutation 1, Colin L Stewart

Primary Identifier  MGI:2177780 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lif
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 3. Northern blot analysis on embryonic fibroblasts isolated from homozygous embryos demonstrated that no detectable transcript was produced from this allele, and cell growth assays confirmed that no functional protein was expressed from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • L-,
  • L-,
  • LIFKO,
  • LIFKO,
  • Lif-,
  • Lif-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

37 Publication categories

Trail: Allele