Primary Identifier | MGI:5285645 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Myh9 |
Inheritance Mode | Semidominant | Transmission | Germline |
Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A cDNA encoding enhanced green fluorescent protein was inserted 5' of the initiating ATG codon in exon 2 and a PGK-neor cassette into intron 2 of the myosin, heavy polypeptide 9, non-muscle (Myh9) gene. The selection cassette has been deleted by Cre recombinase-mediated excision. Immunoblot analysis demonstrates that levels of wild-type and EGFP-tagged MYH9 protein are similar in lungs of heterozygous mutant mice. |