Primary Identifier | MGI:3580272 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Wdr55 |
Transmission | Germline | Strain of Origin | 129S4/SvJae-Tg(Prm-cre)70Og |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Targeting took place in ES cells carrying the cre transgene Tg(Prm-cre)70Og, which expresses Cre recombinase under control of the male-germline specific protamine promoter. The insertion of a floxed neo cassette replaced the 3.7 kb coding region. Cre-mediated excision removed the neo cassette upon transmission from male chimeras. |