Primary Identifier | MGI:7488172 | Allele Type | Endonuclease-mediated |
Attribute String | Modified isoform(s) | Gene | Rorc |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Serine codon 182 (AGT) (in reference to the shorter t isoform) was changed to alanine (GCT) (p.S182A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation prevents phosphorylation of the residue in the encoded peptide. |