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Allele : Rorc<em1Wjmh> RAR-related orphan receptor gamma; endonuclease-mediated mutation 1, Wendy Jia Men Huang

Primary Identifier  MGI:7488172 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Rorc
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Serine codon 182 (AGT) (in reference to the shorter t isoform) was changed to alanine (GCT) (p.S182A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation prevents phosphorylation of the residue in the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • RORgammat<S182A>,
  • RORgammat<S182A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele