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Allele : Tg(CAG-PPARG,-tdTomato)#Sig transgene insertion, Curt D Sigmund

Primary Identifier  MGI:5912197 Allele Type  Transgenic
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter Gene  Tg(CAG-PPARG,-tdTomato)#Sig
Strain of Origin  C57BL/6 x SJL Is Recombinase  false
Is Wild Type  false
molecularNote  The transgenic construct comprised the following elements: a CAG promoter, a loxP site flanked STOP cassette, a splicable intron, the human PPARG coding region (from a cDNA), an IRES in front of the tdTomato reporter gene, a WPRE transcription enhancer and a polyA signal. The construct was injected into the pronuclei of fertilized C57BL/6 x SJL eggs. Only after cre-mediated recombination (which will remove the STOP cassette), will the human and reporter genes be expressed.
  • mutations:
  • Insertion
  • synonyms:
  • PPARgamma-WT,
  • PPARgamma-WT
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories