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Allele : Upf3b<em1(IMPC)Tcp> UPF3 regulator of nonsense transcripts homolog B (yeast); endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156436 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Upf3b
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0565 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of GGAGATCACTTAGTTGGCCT and ATGGCATTTCTTCTACTATA targeting the 5' side and TTATTCACTGCGAACTAATA and TATATCCCCTGAGGCTGTCA targeting the 3' side of exons ENSMUSE00001311515 and ENSMUSE00001291484. This resulted in a 2471-bp deletion of ChrX from 37099863 to 37102333_insTGT (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele