| First Author | Hay JH | Year | 1985 |
| Journal | Lab Anim | Volume | 19 |
| Issue | 2 | Pages | 119-22 |
| PubMed ID | 3889494 | Mgi Jnum | J:27136 |
| Mgi Id | MGI:74554 | Doi | 10.1258/002367785780942561 |
| Citation | Hay JH, et al. (1985) The suitability of immunosuppressed mice kept in a standard animal unit as recipients of human tumour xenografts. Lab Anim 19(2):119-22 |
| abstractText | CBA/Lac mice were immunosuppressed by thymectomy and whole body irradiation with 250 kVp X-rays following pretreatment with cytosine arabinoside. The optimum radiation dose for immunosuppression with prolonged survival was 7.35 Gy. The animals were kept in a standard animal unit with an overall survival rate of 83%. They were found to be suitable for large scale, long-term, xenotransplantation experiments at 20% of the cost of nude mice. |
