| Primary Identifier | MGI:2176219 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Emx1 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | true | Is Wild Type | false |
| description | Three different lines of reporter mice show that Cre activity was restricted to the cerebral cortex and hippocampus, and occurred in 91% of the neurons in the cerebral cortex. |
| molecularNote | A knock-in strategy was used to express cre in an EMX1- specific manner. A lacZ-IRES-cre cassette replaced a segment of the gene containing the first four amino acids of the encoded protein. This allele expresses a bicistronic mRNA encoding beta-galactosidase and Cre recombinase. The endogenous promotor is active in the cerebral cortex and hippocampus. |
