|  Help  |  About  |  Contact Us

Publication : Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

First Author  Sandstedt SA Year  2006
Journal  Mamm Genome Volume  17
Issue  1 Pages  14-21
PubMed ID  16416087 Mgi Jnum  J:104482
Mgi Id  MGI:3612024 Doi  10.1007/s00335-005-0050-y
Citation  Sandstedt SA, et al. (2006) Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus. Mamm Genome 17(1):14-21
abstractText  Two related genes with potentially similar functions, one on the Y chromosome and one on the X chromosome, were examined to determine if they evolved differently because of their chromosomal positions. Six hundred fifty-seven base pairs of coding sequence of Jarid1d (Smcy) on the Y chromosome and Jarid1c (Smcx) on the X chromosome were sequenced in 13 rodent taxa. An analysis of replacement and silent substitutions, using a counting method designed for samples with small evolutionary distances, showed a significant difference between the two genes. The different patterns of replacement and silent substitutions within Jarid1d and Jarid1c may be a result of evolutionary mechanisms that are particularly strong on the Y chromosome because of its unique properties. These findings are similar to results of previous studies of Y chromosomal genes in these and other mammalian taxa, suggesting that genes on the mammalian Y evolve in a chromosome-specific manner.
Quick Links:
 
Quick Links:
 

Expression

Publication --> Expression annotations

 

Other

2 Authors

2 Bio Entities

Trail: Publication

0 Expression