Primary Identifier | MGI:4840264 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Adgra2 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The first coding exon was replaced with a lacZ/neo cassette. Quantitative RT-PCR, northern and western blot analysis confirmed the absence of RNA and protein expression in homozygous embryos. LacZ expression is detected in the vasculature in heterozygous embryos at E10.5. |