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Allele : Emx1<tm1.1(cre)Ito> empty spiracles homeobox 1; targeted mutation 1.1, Shigeyoshi Itohara

Primary Identifier  MGI:3762664 Allele Type  Targeted
Attribute String  Recombinase Gene  Emx1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  true Is Wild Type  false
molecularNote  A cDNA encoding Cre recombinase with an N-terminal nuclear localization signal (nls) resides immediately 5' of the translation initiation site of the endogenous gene. This allele was derived from Emx1tm1(cre)Ito by FLP recombinase excision of a FRT-flanked pgk-neo cassette that lay immediately downstream of the nls-cre gene. The Emx1 promoter drives Cre recombinase expression in the embryonic through adult dorsal telencephelon; deletion of the selection cassette reportedly prevents ectopic expression in other brain regions.
  • mutations:
  • Insertion
  • synonyms:
  • Emx1-Cre KI deltaneo,
  • Emx1<tm2(cre)Ito>,
  • Emx1-Cre KI deltaneo,
  • Emx1<tm2(cre)Ito>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

1 Driven By

Trail: Allele

54 Publication categories

Trail: Allele