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Protein Domain : Nonsense-mediated mRNA decay factor SMG8

Primary Identifier  IPR028802 Type  Family
Short Name  SMG8
description  SMG8 is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. In humans, it is a component of the SMG1C complex composed of SMG1, SMG8 and SMG9 []. SMG-8 can recruit SMG-1 to the mRNA surveillance complex and can regulate the kinase activity of SMG-1 [].

0 Child Features

1 Parent Features

2 Protein Domain Regions