Primary Identifier | IPR028802 | Type | Family |
Short Name | SMG8 |
description | SMG8 is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. In humans, it is a component of the SMG1C complex composed of SMG1, SMG8 and SMG9 []. SMG-8 can recruit SMG-1 to the mRNA surveillance complex and can regulate the kinase activity of SMG-1 []. |