|  Help  |  About  |  Contact Us

Protein Domain : Nonsense-mediated mRNA decay factor SMG8/SMG9

Primary Identifier  IPR019354 Type  Family
Short Name  SMG8/SMG9
description  SMG8 and SMG9 are two subunits of the Smg-1 complex. They suppress Smg-1 kinase activity in the isolated Smg-1 complex, and are involved in nonsense-mediated mRNA decay (NMD) in both mammals and nematodes []. NMD is a surveillance mechanism that detects and degrades mRNAs containing premature translation termination codons.

1 Child Features

0 Parent Features

3 Protein Domain Regions