First Author | Kayano T | Year | 1988 |
Journal | J Biol Chem | Volume | 263 |
Issue | 30 | Pages | 15245-8 |
PubMed ID | 3170580 | Mgi Jnum | J:9395 |
Mgi Id | MGI:57856 | Doi | 10.1016/s0021-9258(19)37577-5 |
Citation | Kayano T, et al. (1988) Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues. J Biol Chem 263(30):15245-8 |
abstractText | Complementary DNA clones encoding a glucose transporter-like protein have been isolated from a human fetal skeletal muscle cDNA library. The 496-amino acid fetal muscle glucose transporter-like protein has 64.4 and 51.6% identity with the previously described human erythrocyte/HepG2 and liver glucose transporter sequences, respectively. RNA blotting studies indicate that transcripts encoding this glucose transporter-like protein are present in most tissues, although their relative abundance varies. The gene encoding this protein has been localized to human chromosome 12p13.3. The identification and characterization of a third human glucose transporter-related protein suggests that there is a family of proteins having similar sequences and structures which are involved in nutrient transport by mammalian cells. |