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Publication : Telomere uncapping, chromosomes, and carcinomas.

First Author  Batista LF Year  2009
Journal  Cancer Cell Volume  15
Issue  6 Pages  455-7
PubMed ID  19477422 Mgi Jnum  J:149513
Mgi Id  MGI:3848627 Doi  10.1016/j.ccr.2009.05.006
Citation  Batista LF, et al. (2009) Telomere uncapping, chromosomes, and carcinomas. Cancer Cell 15(6):455-7
abstractText  Data from mouse models and from human cancers have supported the idea that telomere shortening leads to chromosomal instability and epithelial carcinogenesis. In this issue of Cancer Cell, Else et al. demonstrate that telomere uncapping-altering a protein that protects chromosome ends without shortening telomeres-also results in epithelial cancers.
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