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Allele : Mpc1<tm1.2Mwol> mitochondrial pyruvate carrier 1; targeted mutation 1.2, Michael J Wolfgang

Primary Identifier  MGI:7628164 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mpc1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted around exons 3-5 and an IRES-nls-eYFP, lox511 flanked stop signal, luciferase gene and FRT flanked selection cassette were inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the selection cassette. Cre mediated recombination reomved exons 3-5 and the lox511 flanked stop signal creating a null allele and allowing expression of luciferase.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mpc1<D>,
  • Mpc1<D>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele