Primary Identifier | MGI:5559077 | Allele Type | Targeted |
Attribute String | Constitutively active, Inducible, Inserted expressed sequence, Null/knockout, Reporter | Gene | Hprt1 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Induced With | doxycycline/tetracycline | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The targeting construct introduced into the locus a tetracycline responsive promoter element (tetO), EGFP fused to the Rac1 sequence with a constitutively activating mutation that results in the amino acid substitution of lysine for glutamine at position 61 (Q61L) and a bovine polyadenylation sequence. |