Primary Identifier | MGI:4437305 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Ptk2 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector replaced alternative exons 13 and 14 with an frt flanked hygro cassette and floxed the alternative exon 16. A spontaneous deletion of 307 bp removed exon 15. This deletion is expected to produce a protein lacking the autophosphorylation site tyrosine 397. Production of a truncated protein was confirmed by western blot analysis. |