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Allele : Nes<em1Pqt> nestin; endonuclease-mediated mutation 1, Paul Q Thomas

Primary Identifier  MGI:7447464 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nes
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Exons 1 and 4 were targeted with two sgRNAs (targeting GGAGCTCAATCGACGCCTGG and GCACAGGAGACCCTACTAAA) using CRISPR/Cas9 technology, resulting in an 8 bp deletion in exon 1 (CGCCTGGA chr3:87878561-87878568 (GRCm39)) that creates a reading frame shift and premature stop codon.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Nes FS,
  • Nes FS
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele