| Primary Identifier | MGI:105942 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 15161 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin DNA binding activity. Involved in release from viral latency. Acts upstream of or within blastocyst hatching. Located in cytoplasm and nucleus. Is expressed in early conceptus and secondary oocyte. Used to study methylmalonic acidemia and homocysteinemia cblX type. Human ortholog(s) of this gene implicated in methylmalonic acidemia and homocysteinemia cblX type. Orthologous to human HCFC1 (host cell factor C1). PHENOTYPE: Conditional loss of the maternally inherited allele is embryonic lethal with increased apoptosis and reduced cell proliferation. Liver-specific knockout leads to decreased liver regeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
