| Primary Identifier | MGI:5526090 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence | Gene | Tg(ACTB-KRAS*G12V,-luc)#Lche |
| Strain of Origin | (C57BL/6 x FVB/N)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A transgene consisting of a 1.8 kb chicken beta-actin promoter, a floxed STOP codon, a mutated KRASVAL12, a polyoma virus internal ribosomal re-entry site, and a fusion molecule consisting of chicken ovalbumin, an S-tag and a luciferase molecule. Expression of the constitutively active oncogenic KRASV12 is dependent on Cre-mediated deletion of the STOP codon. The pound symbol (#) is used because a line number was not specified. |
