| Primary Identifier | MGI:1916997 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 69747 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein stabilization. Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be located in nucleus. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure. Orthologous to human ZSWIM7 (zinc finger SWIM-type containing 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit female and male infertility with decreased testis and ovary weights, azoospermia, absent ovarian follicles and impaired chromosomal synapsis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
