Primary Identifier | MGI:2137697 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hadha |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced 1.6kb of sequence containing exon 1, flanking 5' sequences, and part of intron 1. Northern blot analysis of total RNA did not detect mRNA in liver and heart of homozygous mutant newborn pups. Western blot analysis did not detect protein in extracts of liver and heart tissue of homozygous mutant newborn pups. |