Primary Identifier | MGI:2387996 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Zfr |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 6.6 kb region of the gene encoding zinc fingers 1 and 2 was replaced with a promoter-less lacZ-neo cassette via homologous recombination. The mutation results in deletion of 3 exons, disruption of downstream sequences, and fusion of lacZ in-frame to the Zfr sequence. Immunostaining of E5.5 homozygous mutant embryos did not detect gene product. |