Primary Identifier | MGI:1914211 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 66961 |
Mgi Type | lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular component maintenance; nuclear body organization; and response to wounding. Located in paraspeckles. Is active in nucleus. Is expressed in several structures, including Harderian gland; adrenal gland; genitourinary system; gut; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human NEAT1 (nuclear paraspeckle assembly transcript 1). PHENOTYPE: Mice homozygous for a null mutation lack paraspeckles in the nucleus and exhibit reduced pup survival associated with impaired mammary gland development. [provided by MGI curators] |