First Author | Ikeshima-Kataoka H | Year | 2009 |
Journal | In Vivo | Volume | 23 |
Issue | 2 | Pages | 277-80 |
PubMed ID | 19414414 | Mgi Jnum | J:307976 |
Mgi Id | MGI:6727392 | Citation | Ikeshima-Kataoka H, et al. (2009) Cloning and expression of cDNA for interleukin 4 from the MSKR inbred strain of Mus musculus molossinus. In Vivo 23(2):277-80 |
abstractText | The 5'-upsteam region of the genomic gene and cDNA encoding interleukin 4 (IL-4) has been isolated and sequenced from the inbred mouse strain MSKR derived from a Japanese wild mouse using polymerase chain reaction (PCR) methodology. The cDNA sequence of IL-4 of MSKR was found to contain several nucleotide alterations, which result in amino acid substitutions, in comparison with that of inbred mouse BALB/c. In MSKR, IL-4 was expressed at high levels in thymus and spleen as revealed by reverse transcriptase PCR method and Northern hybridization. The tissue-specific expression profile was quite similar to that of laboratory mice. |