Primary Identifier | MGI:1890811 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 328440 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Acts upstream of or within chromatin remodeling. Located in nucleus. Is expressed in early conceptus and ovary. Orthologous to human NPM2 (nucleophosmin/nucleoplasmin 2). PHENOTYPE: Female mice homozygous for disruptions in this gene display reduced fertility. While egg maturation and fertilization are grossly normal, cleavage to the two cell stage or beyond is apparently abnormal. [provided by MGI curators] |