Primary Identifier | MGI:2137851 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ptger4 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced a 1.6kb fragment of the coding region of exon 2, which contains the sixth transmembrane domain of the receptor. Northern blot analysis using a cDNA probe specific for exon 2 did not detect transcript in intestine and spleen homozygous mutant neonates. |