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Allele : Il9<tm1.1(icre)Lky> interleukin 9; targeted mutation 1.1, Richard M Locksley

Primary Identifier  MGI:5927676 Allele Type  Targeted
Attribute String  Null/knockout, Recombinase, Reporter Gene  Il9
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  true Is Wild Type  false
molecularNote  A composite fluorescent reporter/recombinase cassette was introduced to exon 1 of the gene. The targeting vector incorporated rabbit beta-globin (exon 2-3 partial genomic sequence serving as an artificial intron and splicing donor/acceptor), EYFP fluorescent reporter, encephalomyocarditic virus (EMCV) internal ribosome entry site (IRES), P1 phage cre recombinase cDNA optimized for mammalian cells (hCre; iCre), bovine growth hormone (bGH) poly-adenylation signal (pA), and a floxed neomycin resistance cassette. Cre-mediated recombination removed the floxed neo cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IL9<9er>,
  • IL9<9er>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

3 Publication categories