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Publication : c-fos and jun-B mRNAs are transiently expressed in fetal rodent suprachiasmatic nucleus following dopaminergic stimulation.

First Author  Weaver DR Year  1995
Journal  Brain Res Dev Brain Res Volume  85
Issue  2 Pages  293-7
PubMed ID  7600678 Mgi Jnum  J:24540
Mgi Id  MGI:72278 Doi  10.1016/0165-3806(95)00016-7
Citation  Weaver DR, et al. (1995) c-fos and jun-B mRNAs are transiently expressed in fetal rodent suprachiasmatic nucleus following dopaminergic stimulation. Brain Res Dev Brain Res 85(2):293-7
abstractText  We examined the time-course of expression of c-fos and jun-B mRNAs in the fetal rat suprachiasmatic nuclei (SCN) following maternal cocaine injection on gestational day 20. Both c-fos and jun-B mRNA levels increased within 20 min, peaked at 40 min and declined to baseline by 120 min after cocaine treatment (30 mg/kg). In mice, the D1-dopamine agonist, SKF 38393, induced c-fos and jun-B mRNAs in the fetal SCN and striatum. Regulated expression of immediate early genes in the fetal SCN may play a role in entrainment of the fetal clock.
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