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Allele : Drc1<em3Mngx> dynein regulatory complex subunit 1; endonuclease-mediated mutation 2, Mingxi Liu

Primary Identifier  MGI:7294420 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Drc1
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  This gene was targeted for single base substitution using a third generation base editor (BE3). This allele has a mutation of TGGG sequence to TAAA, resulting in a stop-gain at tryptophan 244 (p.W244*). Western blot analysis confirmed the absence of protein expression in testis samples from homozygous mutant males.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Drc1<W244X>,
  • Drc1<W244X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele