Primary Identifier | MGI:7294420 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Drc1 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This gene was targeted for single base substitution using a third generation base editor (BE3). This allele has a mutation of TGGG sequence to TAAA, resulting in a stop-gain at tryptophan 244 (p.W244*). Western blot analysis confirmed the absence of protein expression in testis samples from homozygous mutant males. |