Primary Identifier | MGI:6379578 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Sting1 |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector is designed to insert an FRT-flanked neomycin resistance (neo) cassette downstream of exon 5 of the gene. Exon 6 was modified to harbor mutation (R231H) equivalent to the most common alternative allelic variant of Sting found in humans (R232H). Flp-mediated recombination removed the FRT-flanked neo cassette. |