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Allele : Cabp2<tm1Fha> calcium binding protein 2; targeted mutation 1, Francoise Haeseleer

Primary Identifier  MGI:6157024 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cabp2
Transmission  Germline Strain of Origin  C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Is Recombinase  false Is Wild Type  false
molecularNote  A construct, containing the tdTomato red fluorescent marker gene and a neomycin resistance gene cassette, was inserted immediately downstream of the ATG translation start site in exon 1. The construct replaces the coding region of exon 1 and exon 2a. Stop codons were introduced in all three reading frames of exon 2b. RT-PCR and immunohistochemistry experiments confirmed the lack of transcript and protein expression in the retina from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele