| Primary Identifier | MGI:1858236 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 107934 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in Wnt signaling pathway, planar cell polarity pathway; dopaminergic neuron axon guidance; and serotonergic neuron axon guidance. Acts upstream of or within several processes, including cilium assembly; generation of neurons; and regulation of protein phosphorylation. Is active in glutamatergic synapse; postsynaptic density membrane; and presynaptic active zone membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; epiblast; peripheral nervous system; and retina. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality, abnormal neurvous system development, and abnormal respiratory system development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
