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Publication : From fly head to mammalian forebrain: the story of otd and Otx.

First Author  Finkelstein R Year  1994
Journal  Trends Genet Volume  10
Issue  9 Pages  310-5
PubMed ID  7974744 Mgi Jnum  J:20124
Mgi Id  MGI:68238 Doi  10.1016/0168-9525(94)90033-7
Citation  Finkelstein R, et al. (1994) From fly head to mammalian forebrain: the story of otd and Otx. Trends Genet 10(9):310-5
abstractText  Many of the genes responsible for axial patterning have been conserved throughout evolution. Recent studies of invertebrates and vertebrates are extending our understanding of this molecular conservation into the anterior region of the animal embryo, including the developing brain. These studies suggest that this domain is specified according to a genetic paradigm that is different from that governing trunk development, and are also beginning to provide insights into the structures that underlie the rostral brain.
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