|  Help  |  About  |  Contact Us

Comment :

Type  MGI:General Description  segregation of the paranodal and juxtaparanodal compartments is disrupted in axons, with 73% of nodes of Ranvier in sciatic nerves having a paranode-juxtaparanode overlap phenotype accumulation of electron-dense organelles, mainly mitochondria, in the axoplasm of the paranodal region next to the infolded myelin presence of myelin infoldings at the paranodal regions and these regions often show signs of dys/demyelination and axonal damage non-compacted myelin whorls extend from the compact myelin into the axon, suggesting loss of myelin compaction at the paranodal region