| Primary Identifier | MGI:2652935 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hbb-bh1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exon 1 and exon 2 with a floxed PGK-neo cassette via homologous recombination. The targeted mutation results in deletion of a 1.1 kb of DNA including the promoter region. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of embryonic yolk sac RNA. |
