| Primary Identifier | MGI:4947979 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Orc3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT flanked neo cassette with a 5' loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette leaving exons 5 through 7 floxed. An 84% reduction in protein expression was confirmed by western blot analysis on E13.5 brain extracts |
