First Author | Takami S | Year | 1996 |
Journal | Brain Res | Volume | 707 |
Issue | 2 | Pages | 303-7 |
PubMed ID | 8919310 | Mgi Jnum | J:31485 |
Mgi Id | MGI:78993 | Doi | 10.1016/0006-8993(95)01336-9 |
Citation | Takami S, et al. (1996) An age-dependent novel hyperinnervation of circumvallate papillae by tyrosine hydroxylase-containing nerve fibers in NGF-overexpressing transgenic mice. Brain Res 707(2):303-7 |
abstractText | The density of protein gene product 9.5- and tyrosine hydroxylase-immunoreactive nerve fibers innervating circumvallate papillae of the tongue was substantially increased in transgenic mice that overexpressed nerve growth factor (NGF) when compared with age-matched controls. The fiber density was age-dependent. Only transgenic mice contained NGF-immunoreactive basal cells in the vicinity of taste buds, indicating that target-derived NGF induced novel hyperinnervation of the circumvallate papillae. |