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Protein Domain : Membrane cofactor protein CD46

Primary Identifier  IPR017341 Type  Family
Short Name  CD46
description  This entry represents a group of membrane cofactor proteins (also known as CD46 or TLX). Human CD46 acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue []. Rat CD46 may be involved in the fusion of the spermatozoa with the oocyte during fertilization [].

0 Child Features

0 Parent Features

3 Protein Domain Regions