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Allele : Grm1<m1Btlr> glutamate receptor, metabotropic 1; mutation 1, Bruce Beutler

Primary Identifier  MGI:5688490 Allele Type  Chemically induced (ENU)
Gene  Grm1 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  ENU mutagenesis induced a a C to A transversion at base pair 10,741,508 (v38) on chromosome 10, or base pair 340,870 in the GenBank genomic region NC_000076. The mutation corresponds to residue 1,931 in the NM_016976 mRNA sequence in exon 6 of 9 total exons and residue 1,931 in the NM_001114333 mRNA sequence in exon 6 of 10 total exons. The mutation results in substitution of tyrosine 510 (Y510) for a premature stop codon (Y510*) in all isoforms.
  • mutations:
  • Single point mutation
  • synonyms:
  • donald,
  • donald
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele